BDBM783198 1,1''-(2,2''- ((3R,3''R,6R,6''R)- (((2R,2''R)-(2,2''- ((oxybis(ethane-2,1- diyl))bis(oxy))bis(acetyl)) bis(2- methylpiperazine-4,1- diyl))bis(methylene)) bis(3-methylpiperazine- 6,1- diyl))bis(acetyl))bis(6- (4-fluorobenzyl)-3,3- dimethyl-1,2,3,4- tetrahydro-5H- pyrrolo[3,2-b]pyridin- 5-one)::US20250326771, Compound 6

SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3[nH]c(=O)c(Cc4ccc(F)cc4)cc32)C(CN2CCN(C(=O)COCCOCCOCC(=O)N3CCN(C[C@H]4CN[C@H](C)CN4CC(=O)N4CC(C)(C)c5[nH]c(=O)c(Cc6ccc(F)cc6)cc54)[C@H](C)C3)C[C@H]2C)CN1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 783198   

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783198(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-(2,2'- ((...)
Affinity DataIC50: 5.35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 3 [255-322](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783198(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-(2,2'- ((...)
Affinity DataIC50: 5.35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 2 [269-336](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783198(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-(2,2'- ((...)
Affinity DataIC50: 5.35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 3 [169-235](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783198(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-(2,2'- ((...)
Affinity DataIC50: 522nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 2 [184-250](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783198(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-(2,2'- ((...)
Affinity DataIC50: 522nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783198(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-(2,2'- ((...)
Affinity DataIC50: 3.57E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent