BDBM783351 (S)-4-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dimethyl-5-oxo- 2,3,4,5-tetrahydro-1H- pyrrolo[3,2-b]pyridin- 1-yl)-2-oxoethyl)-5- methylpiperazin-2- yl)methyl)-N-(2-((R)-4- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)-3,3- dimethyl-5-oxo- 2,3,4,5-tetrahydro-1H- pyrrolo[3,2-b]pyridin- 1-yl)-2-oxoethyl)-5- methylpiperazin-2- yl)methyl)-3- methylpiperazin-1-yl)- 2- oxoethyl)morpholine- 2-carboxamide::US20250326771, Compound 159

SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3[nH]c(=O)c(Cc4ccc(F)cc4)cc32)[C@@H](CN2CCO[C@H](C(=O)NCC(=O)N3CCN(C[C@H]4CN[C@H](C)CN4CC(=O)N4CC(C)(C)c5[nH]c(=O)c(Cc6ccc(F)cc6)cc54)[C@H](C)C3)C2)CN1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 783351   

TargetBaculoviral IAP repeat-containing protein 3 [255-322](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783351((S)-4-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dim...)
Affinity DataIC50: 5.35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783351((S)-4-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dim...)
Affinity DataIC50: 15.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 2 [269-336](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783351((S)-4-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dim...)
Affinity DataIC50: 15.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 3 [169-235](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783351((S)-4-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dim...)
Affinity DataIC50: 522nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 2 [184-250](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783351((S)-4-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dim...)
Affinity DataIC50: 522nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783351((S)-4-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dim...)
Affinity DataIC50: 3.57E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent