BDBM783855 (S)-1-(N-(4-(2-chloro-4-fluorophenyl)-1-oxo-1,2-dihydroisoquinolin-7-yl)-N-methyl-L-alanyl)piperidine-3-carboxylic acid::US20250340516, Example 4

SMILES C[C@@H](C(=O)N1CCC[C@H](C(=O)O)C1)N(C)c1ccc2c(-c3ccc(F)cc3Cl)c[nH]c(=O)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783855   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM783855((S)-1-(N-(4-(2-chloro-4-fluorophenyl)-1-oxo-1,2-di...)
Affinity DataIC50: 100nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent