BDBM783957 (R)-1-(2-((4-(2,6-dimethylphenyl)-1-oxo-1,2-dihydroisoquinolin-7-yl)oxy)propanoyl)-4-methylpiperidine-4-carboxylic acid::US20250340516, Example 20

SMILES Cc1cccc(C)c1-c1c[nH]c(=O)c2cc(O[C@H](C)C(=O)N3CCC(C)(C(=O)O)CC3)ccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783957   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM783957((R)-1-(2-((4-(2,6-dimethylphenyl)-1-oxo-1,2-dihydr...)
Affinity DataIC50: 100nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent