BDBM783977 7-(((2R)-1-(8-(2-methoxyethyl)-3,8-diazabicyclo[3.2.1]octan-3-yl)-1-oxopropan-2-yl)oxy)-4-(o-tolyl)isoquinolin-1(2H)-one::US20250340516, Example 27

SMILES COCCN1C2CCC1CN(C(=O)[C@@H](C)Oc1ccc3c(-c4ccccc4C)c[nH]c(=O)c3c1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783977   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM783977(7-(((2R)-1-(8-(2-methoxyethyl)-3,8-diazabicyclo[3....)
Affinity DataIC50: 100nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent