BDBM784645 5-[7-(3,3-difluoro-4,4-dimethyl-pyrrolidin-1-yl)thiazolo[4,5-d]pyrimidin-2-yl]-1H-pyrimidine-2,4-dione::US20250340565, Example 6.1

SMILES CC1(C)CN(c2ncnc3nc(-c4c[nH]c(=O)[nH]c4=O)sc23)CC1(F)F

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784645   

Target5'-nucleotidase [27-547](Human)
AdoRx Therapeutics

US Patent
LigandPNGBDBM784645(5-[7-(3,3-difluoro-4,4-dimethyl-pyrrolidin-1-yl)th...)
Affinity DataIC50: 94nMAssay Description:Compound inhibition of human (h)CD73 (amino acids Trp27-Lys547, R&D Systems 5795-EN-500) enzymatic activity was tested via the Malachite Green Phosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent