BDBM784669 5-[4-(3,3-Difluoro-4-methoxy-pyrrolidin-1-yl)pyrazolo[3,4-d]pyrimidin-2-yl]-1H-pyrimidine-2,4-dione::US20250340565, Example 13.11

SMILES COC1CN(c2ncnc3nn(-c4c[nH]c(=O)[nH]c4=O)cc23)CC1(F)F

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784669   

Target5'-nucleotidase [27-547](Human)
AdoRx Therapeutics

US Patent
LigandPNGBDBM784669(5-[4-(3,3-Difluoro-4-methoxy-pyrrolidin-1-yl)pyraz...)
Affinity DataIC50: 49.2nMAssay Description:Compound inhibition of human (h)CD73 (amino acids Trp27-Lys547, R&D Systems 5795-EN-500) enzymatic activity was tested via the Malachite Green Phosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent