BDBM784694 5-[4-[3,3-difluoro-4-[(4-methylmorpholin-2-yl)methoxy]pyrrolidin-1-yl]pyrazolo[1,5-a]pyrazin-2-yl]-1H-pyrimidine-2,4-dione::US20250340565, Example 25.6

SMILES CN1CCOC(COC2CN(c3nccn4nc(-c5c[nH]c(=O)[nH]c5=O)cc34)CC2(F)F)C1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784694   

Target5'-nucleotidase [27-547](Human)
AdoRx Therapeutics

US Patent
LigandPNGBDBM784694(5-[4-[3,3-difluoro-4-[(4-methylmorpholin-2-yl)meth...)
Affinity DataIC50: 99nMAssay Description:Compound inhibition of human (h)CD73 (amino acids Trp27-Lys547, R&D Systems 5795-EN-500) enzymatic activity was tested via the Malachite Green Phosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent