BDBM785055 N1-(2-((4-((5-bromo-4-((2-carbamoyl-3-fluorophenyl)amino)pyrimidin-2-yl)amino)piperidin-1-yl)sulfonyl)ethyl)-N6((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)adipamide::US12466809, Compound 10

SMILES Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCC(=O)NCCS(=O)(=O)N2CCC(Nc3ncc(Br)c(Nc4cccc(F)c4C(N)=O)n3)CC2)C(C)(C)C)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 785055   

TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
DANA-FARBER CANCER INSTITUTE, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 785055BDBM785055(N1-(2-((4-((5-bromo-4-((2-carbamoyl-3-fluorophenyl...)
Affinity DataIC50: 4.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
DANA-FARBER CANCER INSTITUTE, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 785055BDBM785055(N1-(2-((4-((5-bromo-4-((2-carbamoyl-3-fluorophenyl...)
Affinity DataIC50: 9.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent