BDBM785451 US20250345339, Compound 14

SMILES Cc1cc(Nc2ncnn3ccc(-c4cnn(CCCC(=O)/C=C/CN(C)C)c4)c23)ccc1Oc1ccn2ncnc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 785451   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
IAMBIC THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 785451BDBM785451(US20250345339, Compound 14)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Human)
IAMBIC THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 785451BDBM785451(US20250345339, Compound 14)
Affinity DataIC50: 350nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
IAMBIC THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 785451BDBM785451(US20250345339, Compound 14)
Affinity DataIC50: 3.25E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent