BDBM785453 US20250345339, Compound Zongertinib

SMILES C=CC(=O)NC1CCN(c2ncc3ncnc(Nc4ccc(Oc5ccc6c(c5)ncn6C)c(C)c4)c3n2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 785453   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
IAMBIC THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 785453BDBM785453(US20250345339, Compound Zongertinib)
Affinity DataKi:  94nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
IAMBIC THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 785453BDBM785453(US20250345339, Compound Zongertinib)
Affinity DataKi:  460nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent