BDBM785962 (2S,4R)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)ethyl)-1-((5,5- dioxidodibenzo[b,d] thiophene-3- carbonyl)glycyl)-4- fluoro-4- (fluoromethyl)pyrrolidine- 2-carboxamide::US20250346585, Compound 375

SMILES C[C@@H](NC(=O)[C@@H]1C[C@](F)(CF)CN1C(=O)CNC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1-2)c1cc(C(=N)N)cs1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 785962   

TargetComplement C1s subcomponent(Human)
Alexion Pharmaceuticals, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 785962BDBM785962((2S,4R)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)e...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent