BDBM785963 (S)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)-2-hydroxyethyl)- 7-((9,9-difluoro-9H- fluorene-3- carbonyl)glycyl)-1,4- dioxa-7- azaspiro[4.4]nonane-8- carboxamide::US20250346585, Compound 376

SMILES N=C(N)c1csc([C@@H](CO)NC(=O)[C@@H]2CC3(CN2C(=O)CNC(=O)c2ccc4c(c2)-c2ccccc2C4(F)F)OCCO3)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 785963   

TargetComplement C1s subcomponent(Human)
Alexion Pharmaceuticals, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 785963BDBM785963((S)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)-2-hy...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent