BDBM785972 (2S,4R)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)ethyl)-4- (difluoromethoxy)-1-(2- (1-oxo-5- phenylisoindolin-2- yl)acetyl)pyrrolidine-2- carboxamide::US20250346585, Compound 385

SMILES C[C@@H](NC(=O)[C@@H]1C[C@@H](OC(F)F)CN1C(=O)CN1Cc2cc(-c3ccccc3)ccc2C1=O)c1cc(C(=N)N)cs1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 785972   

TargetComplement C1s subcomponent(Human)
Alexion Pharmaceuticals, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 785972BDBM785972((2S,4R)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)e...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent