BDBM785988 (2S,4R)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)-2-hydroxyethyl)- 1-((9,9-difluoro-9H- fluorene-2- carbonyl)glycyl)-4- fluoro-4- (methoxymethyl) pyrrolidine-2- carboxamide::US20250346585, Compound 397

SMILES COC[C@@]1(F)C[C@@H](C(=O)N[C@H](CO)c2cc(C(=N)N)cs2)N(C(=O)CNC(=O)c2ccc3c(c2)C(F)(F)c2ccccc2-3)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 785988   

TargetComplement C1s subcomponent(Human)
Alexion Pharmaceuticals, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 785988BDBM785988((2S,4R)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)-...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent