BDBM785992 (2S,4R)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)-2-hydroxyethyl)- 1-((9,9-dimethyl-9H- fluorene-3- carbonyl)glycyl)-4- fluoro-4- (fluoromethyl) pyrrolidine-2- carboxamide::US20250346585, Compound 401

SMILES CC1(C)c2ccccc2-c2cc(C(=O)NCC(=O)N3C[C@@](F)(CF)C[C@H]3C(=O)N[C@H](CO)c3cc(C(=N)N)cs3)ccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 785992   

TargetComplement C1s subcomponent(Human)
Alexion Pharmaceuticals, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 785992BDBM785992((2S,4R)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)-...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent