BDBM786014 (2S,4R)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)ethyl)-4- (difluoromethoxy)-1-((9- methyl-9H-fluorene-3- carbonyl)glycyl) pyrrolidine-2- carboxamide::US20250346585, Compound 421

SMILES CC1c2ccccc2-c2cc(C(=O)NCC(=O)N3C[C@H](OC(F)F)C[C@H]3C(=O)N[C@H](C)c3cc(C(=N)N)cs3)ccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 786014   

TargetComplement C1s subcomponent(Human)
Alexion Pharmaceuticals, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786014BDBM786014((2S,4R)-N-((R)-1-(4- carbamimidoylthiophen- 2-yl)e...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent