BDBM786822 2-(7-((2S,5R)-2,5-diethyl-4-(1-(2-methylthiazolo[5,4-b]pyridin-5-yl)ethyl)piperazin-1-yl)-4-(methyl-d3)-5-oxo-4,5-dihydro-2H-pyrazolo[4,3-b]pyridin-2-yl)acetonitrile::US20250346597, Compound A134b

SMILES [2H]C([2H])([2H])n1c(=O)cc(N2C[C@@H](CC)N([C@H](C)c3ccc4nc(C)sc4n3)C[C@@H]2CC)c2nn(CC#N)cc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 786822   

TargetDiacylglycerol kinase zeta(Human)
BEONE MEDICINES I GMBH

US Patent
LigandChemical structure of BindingDB Monomer ID 786822BDBM786822(2-(7-((2S,5R)-2,5-diethyl-4-(1-(2-methylthiazolo[5...)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetDiacylglycerol kinase alpha(Human)
BEONE MEDICINES I GMBH

US Patent
LigandChemical structure of BindingDB Monomer ID 786822BDBM786822(2-(7-((2S,5R)-2,5-diethyl-4-(1-(2-methylthiazolo[5...)
Affinity DataIC50: 108nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent