BDBM787469 3-(4-(((1R)-2,2-Difluorocyclopropyl)methoxy)phenyl)-8-methoxy-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one and 3-(4-(((1S)-2,2-difluorocyclopropyl)methoxy)phenyl)-8-methoxy-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one::US12473289, Example 1-84

SMILES COc4ccn3c(=O)c(c2ccc(OC[C@H]1CC1(F)F)cc2)c(C(F)(F)F)nc3c4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 787469   

TargetAcyl-CoA (8-3)-desaturase(Human)
AMGEN INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 787469BDBM787469(3-(4-(((1R)-2,2-Difluorocyclopropyl)methoxy)phenyl...)
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent