BDBM788114 (1S,2R)-2-Cyanocyclohexyl (8-chloro-::US12473301, Compound 126a

SMILES Cc1c(-c2cc3cc(NC(=O)O[C@H]4CCCC[C@@H]4C#N)ncc3c(Cl)c2F)cnc2c1NCCO2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 788114   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Genentech, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 788114BDBM788114((1S,2R)-2-Cyanocyclohexyl (8-chloro- | US12473301,...)
Affinity DataKi:  492nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent