BDBM788161 US12473303, Compound H-APPAMP-018

SMILES [2H]C([2H])(Nc1cc(NC[C@H]2CCNC[C@@H]2O)nc2c(C(C)C)cnn12)c1cn2ccccc2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 788161   

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Carrick Therapeutics Limited

US Patent
LigandChemical structure of BindingDB Monomer ID 788161BDBM788161(US12473303, Compound H-APPAMP-018)
Affinity DataIC50: 65nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 788161BDBM788161(US12473303, Compound H-APPAMP-018)
Affinity DataIC50: 206nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent