BDBM789853 2-(7-((2S,5R)-4-(1-(2-chlorothieno[3,2-b]pyridin-5-yl)ethyl)-2,5-diethylpiperazin-1-yl)-4-methyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)acetonitrile::US20250353858, Compound A44a

SMILES CC[C@H]1CN([C@@H](C)c2ccc3sc(Cl)cc3n2)[C@H](CC)CN1c1cc(=O)n(C)c2cc(CC#N)nn12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 789853   

TargetDiacylglycerol kinase alpha(Human)
BEONE MEDICINES I GMBH

US Patent
LigandChemical structure of BindingDB Monomer ID 789853BDBM789853(2-(7-((2S,5R)-4-(1-(2-chlorothieno[3,2-b]pyridin-5...)
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDiacylglycerol kinase zeta(Human)
BEONE MEDICINES I GMBH

US Patent
LigandChemical structure of BindingDB Monomer ID 789853BDBM789853(2-(7-((2S,5R)-4-(1-(2-chlorothieno[3,2-b]pyridin-5...)
Affinity DataIC50: 691nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent