BDBM789890 2-(4-((2S,5R)-4-(1-(2-cyclopropylpyrazolo[1,5-a]pyrimidin-5-yl)ethyl)-2,5-diethylpiperazin-1-yl)-1-methyl-2-oxo-1,2-dihydropyrazolo[1,5-a][1,3,5]triazin-7-yl)acetonitrile::US20250353858, Compound A54b

SMILES CC[C@H]1CN([C@H](C)c2ccn3nc(C4CC4)cc3n2)[C@H](CC)CN1c1nc(=O)n(C)c2cc(CC#N)nn12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 789890   

TargetDiacylglycerol kinase zeta(Human)
BEONE MEDICINES I GMBH

US Patent
LigandChemical structure of BindingDB Monomer ID 789890BDBM789890(2-(4-((2S,5R)-4-(1-(2-cyclopropylpyrazolo[1,5-a]py...)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDiacylglycerol kinase alpha(Human)
BEONE MEDICINES I GMBH

US Patent
LigandChemical structure of BindingDB Monomer ID 789890BDBM789890(2-(4-((2S,5R)-4-(1-(2-cyclopropylpyrazolo[1,5-a]py...)
Affinity DataIC50: 69nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent