BDBM789968 2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,13-hexahydro-14H-3,5- ethenotripyrazolo[3,4-f:3'',4''-j:4$#8243;,3$#8243;- n][1,4]oxazacyclopentadecin-14- yl]ethan-1-ol::US20250353864, Example 61

SMILES Cc1nn(CCO)c2c1/C=C/c1n[nH]c3ccc(cc13)-c1cnn(C)c1O[C@@H](C)CN(C)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 789968   

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 0.0600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 0.170nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 0.210nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 0.290nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 0.760nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 1.08nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 1.23nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 1.96nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 6.19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 9.21nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 21.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent