BDBM790007 2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2,8,10,11,12,13- hexahydro-14H-3,5- ethenotripyrazolo[3,4-f:3'',4''-j:4$#8243;,3$#8243;- n][1,4]oxazacyclopentadecin-14- yl]ethan-1-ol::US20250353864, Example 114

SMILES CC(=N)C1=C(\NCCO)CN(C(C)C)C[C@H](C)Oc2c(cnn2C)-c2ccc3[nH]nc(c3c2)\C=C\1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 790007   

TargetEpidermal growth factor receptor [L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.110nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.120nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.170nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.230nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.380nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.460nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.910nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.920nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.980nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 20.9nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent