BDBM790036 2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)oxy]-2,8,10,11,12,13- hexahydro-14H-3,5- ethenotripyrazolo[3,4-f:3'',4''-j:4$#8243;,3$#8243;- n][1,4]oxazacyclopentadecin-14- yl}ethan-1-ol::US20250353864, Example 147

SMILES CC(C)OC(=N)C1=C(\NCCO)CN(C)C[C@H](C)Oc2c(cnn2C)-c2ccc3[nH]nc(c3c2)\C=C\1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 790036   

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.0200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.110nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.130nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.190nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.320nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.390nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.440nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.590nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetALK tyrosine kinase receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.990nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 3.16nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 5.21nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 9.08nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent