BDBM790038 (10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-yl]oxy}- 8,10,12,14-tetramethyl-2,10,11,12,13,14- hexahydro-8H-3,5-ethenotripyrazolo[3,4- f:3'',4''-j:4$#8243;,3$#8243;- n][1,4]oxazacyclopentadecine::US20250353864, Example 150

SMILES C=S(C)(=O)N6CC(Oc2nn(C)c3CN(C)C[C@H](C)Oc1c(cnn1C)c5ccc4[nH]nc(/C=C\c23)c4c5)C6

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 790038   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790038BDBM790038((10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-yl]o...)
Affinity DataIC50: 0.370nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790038BDBM790038((10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-yl]o...)
Affinity DataIC50: 0.450nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790038BDBM790038((10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-yl]o...)
Affinity DataIC50: 2.31nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790038BDBM790038((10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-yl]o...)
Affinity DataIC50: 2.58nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790038BDBM790038((10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-yl]o...)
Affinity DataIC50: 3.21nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790038BDBM790038((10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-yl]o...)
Affinity DataIC50: 6.36nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790038BDBM790038((10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-yl]o...)
Affinity DataIC50: 33.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent