BDBM790106 2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,11,17-hexahydro-6H-14,16- ethenotripyrazolo[3,4-f:3'',4''-j:4$#8243;,3$#8243;- n]pyrrolo[2,1- c][1,4]oxazacyclopentadecin-3(4H)- yl]ethan-1-ol::US20250353864, Example 241

SMILES CCOc1nn(CCO)c2c1/C=C/c1n[nH]c3ccc(cc13)-c1cnn(C)c1O[C@H](C)[C@H]1CCCN1C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 790106   

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.130nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.150nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.180nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.180nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.190nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.230nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.270nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.280nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.310nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.520nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.730nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent