BDBM790134 (17E)-8,14-dimethyl-2,8,10,11,13,14- hexahydro-3,5- etheno[1,4]dioxacyclopentadecino[10,11- c:15,14-c'':6,7-c$#8243;]tripyrazole-16- carbonitrile::US20250353864, Example 302

SMILES Cn1nc(C#N)c2c1COCCOc1c(cnn1C)-c1ccc3[nH]nc(c3c1)/C=C/2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 790134   

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790134BDBM790134((17E)-8,14-dimethyl-2,8,10,11,13,14- hexahydro-3,5...)
Affinity DataIC50: 1.19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790134BDBM790134((17E)-8,14-dimethyl-2,8,10,11,13,14- hexahydro-3,5...)
Affinity DataIC50: 1.23nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790134BDBM790134((17E)-8,14-dimethyl-2,8,10,11,13,14- hexahydro-3,5...)
Affinity DataIC50: 1.33nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetALK tyrosine kinase receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790134BDBM790134((17E)-8,14-dimethyl-2,8,10,11,13,14- hexahydro-3,5...)
Affinity DataIC50: 19.9nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790134BDBM790134((17E)-8,14-dimethyl-2,8,10,11,13,14- hexahydro-3,5...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent