BDBM790136 (17E)-8,16-dimethyl-2,8,10,11- tetrahydro-13H-3,5- ethenodipyrazolo[3'',4'':10,11;4$#8243;,3$#8243;:14,15] [1,4]dioxacyclopentadecino[6,7- c][1,2]oxazole::US20250353864, Example 320

SMILES Cc1onc2c1/C=C/c1n[nH]c3ccc(cc13)-c1cnn(C)c1OCCOC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 790136   

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790136BDBM790136((17E)-8,16-dimethyl-2,8,10,11- tetrahydro-13H-3,5-...)
Affinity DataIC50: 0.155nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790136BDBM790136((17E)-8,16-dimethyl-2,8,10,11- tetrahydro-13H-3,5-...)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790136BDBM790136((17E)-8,16-dimethyl-2,8,10,11- tetrahydro-13H-3,5-...)
Affinity DataIC50: 0.324nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetALK tyrosine kinase receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790136BDBM790136((17E)-8,16-dimethyl-2,8,10,11- tetrahydro-13H-3,5-...)
Affinity DataIC50: 32.2nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790136BDBM790136((17E)-8,16-dimethyl-2,8,10,11- tetrahydro-13H-3,5-...)
Affinity DataIC50: 69.7nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent