BDBM790139 (17E)-8,14,16-trimethyl-2,8,9,11,12,14- hexahydro-3,5- etheno[1,4]dioxacyclopentadecino[11,10- c:15,14-c'':6,7-c$#8243;]tripyrazole::US20250353864, Example 6

SMILES Cc1nn(C)c2c1/C=C/c1n[nH]c3ccc(cc13)-c1cnn(C)c1COCCO2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 790139   

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790139BDBM790139((17E)-8,14,16-trimethyl-2,8,9,11,12,14- hexahydro-...)
Affinity DataIC50: 0.230nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790139BDBM790139((17E)-8,14,16-trimethyl-2,8,9,11,12,14- hexahydro-...)
Affinity DataIC50: 0.340nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790139BDBM790139((17E)-8,14,16-trimethyl-2,8,9,11,12,14- hexahydro-...)
Affinity DataIC50: 0.520nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790139BDBM790139((17E)-8,14,16-trimethyl-2,8,9,11,12,14- hexahydro-...)
Affinity DataIC50: 178nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent