BDBM790140 1-[(17E)-8,15,16-trimethyl- 2,8,10,11,13,15-hexahydro-12H-3,5- ethenotripyrazolo[3,4-f:3'',4''-j:4$#8243;,3$#8243;- n][1,4]oxazacyclopentadecin-12- yl]ethan-1-one::US20250353864, Example 52

SMILES CC(=O)N1CCOc2c(cnn2C)-c2ccc3[nH]nc(c3c2)/C=C/c2c(nn(C)c2C)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 790140   

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790140BDBM790140(1-[(17E)-8,15,16-trimethyl- 2,8,10,11,13,15-hexahy...)
Affinity DataIC50: 0.190nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790140BDBM790140(1-[(17E)-8,15,16-trimethyl- 2,8,10,11,13,15-hexahy...)
Affinity DataIC50: 0.240nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790140BDBM790140(1-[(17E)-8,15,16-trimethyl- 2,8,10,11,13,15-hexahy...)
Affinity DataIC50: 0.560nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790140BDBM790140(1-[(17E)-8,15,16-trimethyl- 2,8,10,11,13,15-hexahy...)
Affinity DataIC50: 148nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent