BDBM790143 (10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,13-hexahydro-3,5- ethenodipyrazolo[3,4-j:4'',3''- n][1,2]thiazolo[3,4- f][1,4]oxazacyclopentadecine::US20250353864, Example 158

SMILES Cc1snc2c1/C=C/c1n[nH]c3ccc(cc13)-c1cnn(C)c1O[C@@H](C)CN(C)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 790143   

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790143BDBM790143((10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,13-...)
Affinity DataIC50: 0.140nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790143BDBM790143((10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,13-...)
Affinity DataIC50: 0.310nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790143BDBM790143((10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,13-...)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790143BDBM790143((10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,13-...)
Affinity DataIC50: 664nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent