BDBM790144 (10S,17E)-14-(2-hydroxyethyl)-8,10,12- trimethyl-2,10,11,12,13,14-hexahydro- 8H-3,5-ethenotripyrazolo[3,4-f:3'',4''- j:4$#8243;,3$#8243;-n][1,4]oxazacyclopentadecine-16- carbonitrile::US20250353864, Example 208

SMILES C[C@H]1CN(C)Cc2c(c(C#N)nn2CCO)/C=C/c2n[nH]c3ccc(cc23)-c2cnn(C)c2O1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 790144   

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790144BDBM790144((10S,17E)-14-(2-hydroxyethyl)-8,10,12- trimethyl-2...)
Affinity DataIC50: 0.130nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790144BDBM790144((10S,17E)-14-(2-hydroxyethyl)-8,10,12- trimethyl-2...)
Affinity DataIC50: 0.590nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790144BDBM790144((10S,17E)-14-(2-hydroxyethyl)-8,10,12- trimethyl-2...)
Affinity DataIC50: 1.53nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790144BDBM790144((10S,17E)-14-(2-hydroxyethyl)-8,10,12- trimethyl-2...)
Affinity DataIC50: 220nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent