BDBM791903 (E)-3-((2R,3S)-3-hydroxy-2-methyl-4-oxo-2,3,4,5-tetrahydro-1H-pyrido[2,3-b][1,4]diazepin-8-yl)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)acrylamide ::US12545672, Compound 150

SMILES Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)N[C@H](C)[C@H](O)C(=O)N3)oc2ccccc12

InChI Key InChIKey=YEFHSSWFLULRED-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791903   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH]()
Debiopharm International

US Patent
LigandChemical structure of BindingDB Monomer ID 791903BDBM791903((E)-3-((2R,3S)-3-hydroxy-2-methyl-4-oxo-2,3,4,5-te...)
Affinity DataIC50: 10nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/22/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH]()
Debiopharm International

US Patent
LigandChemical structure of BindingDB Monomer ID 791903BDBM791903((E)-3-((2R,3S)-3-hydroxy-2-methyl-4-oxo-2,3,4,5-te...)
Affinity DataIC50: 1.00E+3nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/22/2026
Entry Details
US Patent