BDBM792939 2-(4-phenoxyphenyl)-8-(1-propioloylpiperidin-4-yl)-5,6,7,8-tetrahydroimidazo[1,2-b]pyridazine-3-carboxamide::US12552798, Example 11

SMILES C#CC(=O)N1CCC(C2CCNn3c2nc(-c2ccc(Oc4ccccc4)cc2)c3C(N)=O)CC1

InChI Key InChIKey=JGNAYZOUQHXHET-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 792939   

TargetTyrosine-protein kinase BTK(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792939BDBM792939(2-(4-phenoxyphenyl)-8-(1-propioloylpiperidin-4-yl)...)
Affinity DataIC50: 8.20nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792939BDBM792939(2-(4-phenoxyphenyl)-8-(1-propioloylpiperidin-4-yl)...)
Affinity DataIC50: 22.8nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792939BDBM792939(2-(4-phenoxyphenyl)-8-(1-propioloylpiperidin-4-yl)...)
Affinity DataIC50: 28.1nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792939BDBM792939(2-(4-phenoxyphenyl)-8-(1-propioloylpiperidin-4-yl)...)
Affinity DataIC50: 225nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent