BDBM792942 (E)-2-(4-(4-fluorophenoxy)phenyl)-8-(1-(4,4,4-trifluorobut-2-enoyl)piperidin-4-yl)-5,6,7,8-tetrahydroimidazo[1,2-b]pyridazine-3-carboxamide::US12552798, Example 14

SMILES NC(=O)c1c(-c2ccc(Oc3ccc(F)cc3)cc2)nc2n1NCCC2C1CCN(C(=O)/C=C/C(F)(F)F)CC1

InChI Key InChIKey=HRKRIUVBTPPMER-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 792942   

TargetTyrosine-protein kinase BTK(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792942BDBM792942((E)-2-(4-(4-fluorophenoxy)phenyl)-8-(1-(4,4,4-trif...)
Affinity DataIC50: 61.5nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent