BDBM792943 8-(1-acryloylpiperidin-4-yl)-2-(4-(4-methoxyphenoxy)phenyl)-5,6,7,8-tetrahydroimidazo[1,2-b]pyridazine-3-carboxamide::US12552798, Example 15

SMILES C=CC(=O)N1CCC(C2CCNn3c2nc(-c2ccc(Oc4ccc(OC)cc4)cc2)c3C(N)=O)CC1

InChI Key InChIKey=ILOZQWFLUUKWAV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 792943   

TargetTyrosine-protein kinase BTK(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792943BDBM792943(8-(1-acryloylpiperidin-4-yl)-2-(4-(4-methoxyphenox...)
Affinity DataIC50: 42.6nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent