BDBM792945 (E)-2-(4-(4-methoxyphenoxy)phenyl)-8-(1-(4,4,4-trifluorobut-2-enoyl)piperidin-4-yl)-5,6,7,8-tetrahydroimidazo[1,2-b]pyridazine-3-carboxamide::US12552798, Example 17

SMILES COc1ccc(Oc2ccc(-c3nc4n(c3C(N)=O)NCCC4C3CCN(C(=O)/C=C/C(F)(F)F)CC3)cc2)cc1

InChI Key InChIKey=AOHDSDGIPZZXQX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 792945   

TargetTyrosine-protein kinase BTK(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792945BDBM792945((E)-2-(4-(4-methoxyphenoxy)phenyl)-8-(1-(4,4,4-tri...)
Affinity DataIC50: 212nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent