BDBM792954 7-(1-acryloylpiperidin-4-yl)-2-(3-methoxy-4-phenoxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole-3-carboxamide::US12552798, Example 28

SMILES C=CC(=O)N1CCC(C2CCn3c2nc(-c2ccc(Oc4ccccc4)c(OC)c2)c3C(N)=O)CC1

InChI Key InChIKey=VLQAQKJSBAKZKC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 792954   

TargetTyrosine-protein kinase BTK(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792954BDBM792954(7-(1-acryloylpiperidin-4-yl)-2-(3-methoxy-4-phenox...)
Affinity DataIC50: 10.7nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792954BDBM792954(7-(1-acryloylpiperidin-4-yl)-2-(3-methoxy-4-phenox...)
Affinity DataIC50: 80.3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792954BDBM792954(7-(1-acryloylpiperidin-4-yl)-2-(3-methoxy-4-phenox...)
Affinity DataIC50: 382nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Henan Zhiwei Biomedicine Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 792954BDBM792954(7-(1-acryloylpiperidin-4-yl)-2-(3-methoxy-4-phenox...)
Affinity DataIC50: 3.00E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent