BDBM792958 5-amino-2-(3,3-difluoropropyl)-8-[(cis)-2,6-dimethylmorpholin-4-yl]-7-phenyl-[1,2,4]triazolo[4,3-c]pyrimidin-3-one::US12552799, Example 1-3

SMILES C[C@@H]1CN(c2c(-c3ccccc3)nc(N)n3c(=O)n(CCC(F)F)nc23)C[C@H](C)O1

InChI Key InChIKey=KTEUQRPEFHJWKI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 792958   

TargetAdenosine receptor A2a(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792958BDBM792958(5-amino-2-(3,3-difluoropropyl)-8-[(cis)-2,6-dimeth...)
Affinity DataKi:  79.4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetAdenosine receptor A1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792958BDBM792958(5-amino-2-(3,3-difluoropropyl)-8-[(cis)-2,6-dimeth...)
Affinity DataKi: >3.98E+3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent