BDBM792969 5-amino-8-[(cis)-2,6-dimethylmorpholin-4-yl]-2-[(5-fluoro-2-pyridyl)methyl]-7-phenyl-[1,2,4]triazolo[4,3-c]pyrimidin-3-one::US12552799, Example 1-14

SMILES C[C@@H]1CN(c2c(-c3ccccc3)nc(N)n3c(=O)n(Cc4ccc(F)cn4)nc23)C[C@H](C)O1

InChI Key InChIKey=QKJISDGJUZBGJQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 792969   

TargetAdenosine receptor A2a(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792969BDBM792969(5-amino-8-[(cis)-2,6-dimethylmorpholin-4-yl]-2-[(5...)
Affinity DataKi:  12.6nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetAdenosine receptor A1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792969BDBM792969(5-amino-8-[(cis)-2,6-dimethylmorpholin-4-yl]-2-[(5...)
Affinity DataKi:  1.26E+3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetCannabinoid receptor 1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792969BDBM792969(5-amino-8-[(cis)-2,6-dimethylmorpholin-4-yl]-2-[(5...)
Affinity DataKi:  9.50E+3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent