BDBM792970 5-amino-8-[(cis)-2,6-dimethylmorpholin-4-yl]-2-[(2-methoxy-3-pyridyl)methyl]-7-phenyl-[1,2,4]triazolo[4,3-c]pyrimidin-3-one::US12552799, Example 1-15

SMILES COc1ncccc1Cn1nc2c(N3C[C@@H](C)O[C@@H](C)C3)c(-c3ccccc3)nc(N)n2c1=O

InChI Key InChIKey=LEMDGRRAFOZAHN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 792970   

TargetAdenosine receptor A2a(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792970BDBM792970(5-amino-8-[(cis)-2,6-dimethylmorpholin-4-yl]-2-[(2...)
Affinity DataKi:  3.98nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetAdenosine receptor A1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792970BDBM792970(5-amino-8-[(cis)-2,6-dimethylmorpholin-4-yl]-2-[(2...)
Affinity DataKi:  398nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent