BDBM792973 5-amino-8-[(cis)-2,6-dimethyl-3,6-dihydro-2H-pyran-4-yl]-7-phenyl-2-(3,3,3-trifluoropropyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3-one::US12552799, Example 2-1

SMILES C[C@@H]1CC(c2c(-c3ccccc3)nc(N)n3c(=O)n(CCC(F)(F)F)nc23)=C[C@H](C)O1

InChI Key InChIKey=OXTRSOVDEBIWBM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 792973   

TargetAdenosine receptor A2a(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792973BDBM792973(5-amino-8-[(cis)-2,6-dimethyl-3,6-dihydro-2H-pyran...)
Affinity DataKi:  2.51nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetAdenosine receptor A1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792973BDBM792973(5-amino-8-[(cis)-2,6-dimethyl-3,6-dihydro-2H-pyran...)
Affinity DataKi:  501nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetCannabinoid receptor 1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792973BDBM792973(5-amino-8-[(cis)-2,6-dimethyl-3,6-dihydro-2H-pyran...)
Affinity DataKi:  3.15E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent