BDBM792976 5-amino-7-(4-fluorophenyl)-8-(4-methyl-1,3-benzoxazol-6-yl)-2-(3,3,3-trifluoropropyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3-one::US12552799, Example 4-1

SMILES Cc1cc(-c2c(-c3ccc(F)cc3)nc(N)n3c(=O)n(CCC(F)(F)F)nc23)cc2ocnc12

InChI Key InChIKey=GUGRLSDYHRPSDJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 792976   

TargetAdenosine receptor A2a(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792976BDBM792976(5-amino-7-(4-fluorophenyl)-8-(4-methyl-1,3-benzoxa...)
Affinity DataKi:  0.501nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetAdenosine receptor A1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792976BDBM792976(5-amino-7-(4-fluorophenyl)-8-(4-methyl-1,3-benzoxa...)
Affinity DataKi:  316nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetCannabinoid receptor 1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792976BDBM792976(5-amino-7-(4-fluorophenyl)-8-(4-methyl-1,3-benzoxa...)
Affinity DataKi:  3.70E+3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent