BDBM792978 5-amino-7-(4-fluorophenyl)-8-(4-methyl-1,3-benzoxazol-6-yl)-2-[(5-methyl-2-pyridyl)methyl]-[1,2,4]triazolo[4,3-c]pyrimidin-3-one::US12552799, Example 4-3

SMILES Cc1ccc(Cn2nc3c(-c4cc(C)c5ncoc5c4)c(-c4ccc(F)cc4)nc(N)n3c2=O)nc1

InChI Key InChIKey=YCLLBMADBFTBBS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 792978   

TargetAdenosine receptor A2a(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792978BDBM792978(5-amino-7-(4-fluorophenyl)-8-(4-methyl-1,3-benzoxa...)
Affinity DataKi:  0.158nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetAdenosine receptor A1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792978BDBM792978(5-amino-7-(4-fluorophenyl)-8-(4-methyl-1,3-benzoxa...)
Affinity DataKi:  126nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent