BDBM792980 5-amino-2-[(5-fluoro-2-pyridyl)methyl]-8-(7-methyl-1H-benzimidazol-5-yl)-7-phenyl-[1,2,4]triazolo[4,3-c]pyrimidin-3-one::US12552799, Example 4-5

SMILES Cc1cc(-c2c(-c3ccccc3)nc(N)n3c(=O)n(Cc4ccc(F)cn4)nc23)cc2nc[nH]c12

InChI Key InChIKey=OFFURUJZFMFNSK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 792980   

TargetAdenosine receptor A2a(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792980BDBM792980(5-amino-2-[(5-fluoro-2-pyridyl)methyl]-8-(7-methyl...)
Affinity DataKi:  1nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetAdenosine receptor A1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792980BDBM792980(5-amino-2-[(5-fluoro-2-pyridyl)methyl]-8-(7-methyl...)
Affinity DataKi:  100nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetCannabinoid receptor 1(Human)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 792980BDBM792980(5-amino-2-[(5-fluoro-2-pyridyl)methyl]-8-(7-methyl...)
Affinity DataKi:  2.44E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent