BDBM793138 US20260049071, No. I-119

SMILES O=C(NC1CC1)c1cc(F)ccc1Sc1ccc2c(/C=C/c3cc(CCCN4CCCC4)ccn3)n[nH]c2c1

InChI Key InChIKey=NXJMYROMMOSCDK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 793138   

TargetVascular endothelial growth factor receptor 2(Human)
Beyang Therapeutics Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793138BDBM793138(US20260049071, No. I-119)
Affinity DataIC50: 1nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details US Patent

TargetVascular endothelial growth factor receptor 1(Human)
Beyang Therapeutics Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793138BDBM793138(US20260049071, No. I-119)
Affinity DataIC50: 5.5nMAssay Description:This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details US Patent

TargetVascular endothelial growth factor receptor 3(Human)
Beyang Therapeutics Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793138BDBM793138(US20260049071, No. I-119)
Affinity DataIC50: 55nMAssay Description:Compounds (as well as stereoisomer(s) thereof and/or salt(s) thereof) were tested for CX3CR1 agonism in a cell based assay with fluorescent readout i...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
Beyang Therapeutics Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793138BDBM793138(US20260049071, No. I-119)
Affinity DataIC50: 6.00E+4nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details US Patent