BDBM794047 5-(3-isopropoxy-1-methyl-pyrazolo[3,4-c]pyridazin-5-yl)-1H-pyrimidine-2,4-dione::US20260055113, Example 8

SMILES CC(C)Oc1nn(C)c2nnc(-c3c[nH]c(=O)[nH]c3=O)cc12

InChI Key InChIKey=RQHSYRMDKSVDSX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 794047   

Target5'-nucleotidase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 794047BDBM794047(5-(3-isopropoxy-1-methyl-pyrazolo[3,4-c]pyridazin-...)
Affinity DataIC50: 3.88nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details US Patent