BDBM794049 5-[1-methyl-3-[(1S)-1-(2-pyridyl)ethoxy]pyrazolo[3,4-c]pyridazin-5-yl]-1H-pyrimidine-2,4-dione::US20260055113, Example 26

SMILES C[C@H](Oc1nn(C)c2nnc(-c3c[nH]c(=O)[nH]c3=O)cc12)c1ccccn1

InChI Key InChIKey=DFBZHDUKLMCACO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 794049   

Target5'-nucleotidase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 794049BDBM794049(5-[1-methyl-3-[(1S)-1-(2-pyridyl)ethoxy]pyrazolo[3...)
Affinity DataIC50: 0.330nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details US Patent